Empathogens or entactogens are research chemicals that enhance empathy between people. They are in some terms species, in others—relatives of psychedelics. Empathogens include substances such as MDMA (commonly known as Ecstasy) and MDA. Mephedrone and methamphetamine also have this property. The empathogen term was proposed in 1983 by Ralph Metzner, to refer to chemical agents that evoke a empathy feeling. The related entactogen term was proposed by David E. Nichols, as an alternative to the term empathogen, in order to avoid negative associations with the Greek root "pathos" (suffering).

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